M3808

MRS 2179 ammonium salt hydrate

≥98% (HPLC)

• Synonym(s): 2′-Deoxy-N⁶-methyl adenosine 3′,5′-diphosphate diammonium salt
• Empirical Formula (Hill Notation): C₁₁H₁₇N₅O₉P₂ · xNH₃ · yH₂O
• CAS Number: 101204-49-3
• Molecular Weight: 425.23 (anhydrous free acid basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278551
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• storage condition: desiccated
• solubility: DMSO: 1.1 mg/mL; H₂O: >10 mg/mL
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: N.O.CNc1ncnc2n(cnc12)[C@H]3C[C@H](OP(O)(O)=O)[C@@H](COP(O)(O)=O)O3
• InChI: 1S/C11H17N5O9P2.H3N.H2O/c1-12-10-9-11(14-4-13-10)16(5-15-9)8-2-6(25-27(20,21)22)7(24-8)3-23-26(17,18)19;;/h4-8H,2-3H2,1H3,(H,12,13,14)(H2,17,18,19)(H2,20,21,22);1H3;1H2/t6-,7+,8+;;/m0../s1
• InChI key: DEQIORFOBOEGKZ-ZJWYQBPBSA-N
• Gene Information: human ... P2RY1(5028)

Description

Application

MRS 2179 ammonium salt hydrate has been used as a P2Y1 receptor antagonist in porcine coronary small arteries, endothelial cells, and hippocampal astrocytes.

Biochem/physiol Actions

Competitive P2Y₁ purinoceptor antagonist.

MRS 2179 resists localized venous thrombosis and is useful in treating thrombotic syndromes due to its platelet aggregation inhibition functionality.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves