N158

Naftopidil hydrochloride hydrate

solid

• Synonym(s): 4-(2-Methoxyphenyl)-α-[(1-naphthalenyloxy)methyl]-1-piperazineethanol hydrochloride hydrate, KT-611
• Empirical Formula (Hill Notation): C₂₄H₂₈N₂O₃ · xHCl · yH₂O
• CAS Number: 57149-07-2
• Molecular Weight: 392.49 (anhydrous free base basis)
• MDL number: MFCD11046013
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277790
• NACRES: NA.77

Properties

• form: solid
• Quality Level: 200
• color: white
• solubility: methanol: >10 mg/mL; H₂O: insoluble
• SMILES string: O.Cl.COc1ccccc1N2CCN(CC2)CC(O)COc3cccc4ccccc34
• InChI: 1S/C24H28N2O3.ClH.H2O/c1-28-24-11-5-4-10-22(24)26-15-13-25(14-16-26)17-20(27)18-29-23-12-6-8-19-7-2-3-9-21(19)23;;/h2-12,20,27H,13-18H2,1H3;1H;1H2
• InChI key: INIDYCYXDNFBSV-UHFFFAOYSA-N
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Description

Biochem/physiol Actions

α₁-Adrenoceptor antagonist; antihypertensive.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves