N6037

Neridronate

≥97% (NMR), solid, bone resorption inhibitor

• Synonym(s): 6-Amino-1-hydroxyhexylidene bisphosphonic acid, Neridronic acid, Nerixia
• Empirical Formula (Hill Notation): C₆H₁₇NO₇P₂
• CAS Number: 79778-41-9
• Molecular Weight: 277.15
• MDL number: MFCD00866995
• UNSPSC Code: 51111800
• PubChem Substance ID: 24724553
• NACRES: NA.77

Properties

• Product Name: Neridronate, ≥97% (NMR), solid
• description: may contain <1% (w/w) inorganic salts
• Quality Level: 100
• Assay: ≥97% (NMR)
• form: solid
• color: white
• solubility: H₂O: >5 mg/mL
• storage temp.: 2-8°C
• SMILES string: NCCCCCC(O)(P(O)(O)=O)P(O)(O)=O
• InChI: 1S/C6H17NO7P2/c7-5-3-1-2-4-6(8,15(9,10)11)16(12,13)14/h8H,1-5,7H2,(H2,9,10,11)(H2,12,13,14)
• InChI key: PUUSSSIBPPTKTP-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Neridronate is a bone resorption inhibitor. It is used to treat Osteogenesis Imperfecta, an "orphan disease" characterized by a fragility of the bone enough to be named the "illness of bones of crystal".

Neridronate is a bone resorption inhibitor. It is used to treat Osteogenesis Imperfecta.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves