P3490

Ponasterone A

≥65%

• Synonym(s): 2β,3β,14α,20R,22R-Pentahydroxy-5β-cholest-7-en-6-one, 25-Deoxy-20-hydroxyecdysone, 25-Deoxyecdysterone
• Empirical Formula (Hill Notation): C₂₇H₄₄O₆
• CAS Number: 13408-56-5
• Molecular Weight: 464.63
• MDL number: MFCD00272144
• UNSPSC Code: 51111800
• PubChem Substance ID: 329820175
• NACRES: NA.77

Properties

• biological source: synthetic (organic)
• Quality Level: 200
• sterility: non-sterile
• form: powder
• concentration: ≥65%
• solubility: ethanol: soluble
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: CC(C)CC[C@@H](O)[C@](C)(O)[C@H]1CC[C@@]2(O)C3=CC(=O)[C@@H]4C[C@@H](O)[C@@H](O)C[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C27H44O6/c1-15(2)6-7-23(31)26(5,32)22-9-11-27(33)17-12-19(28)18-13-20(29)21(30)14-24(18,3)16(17)8-10-25(22,27)4/h12,15-16,18,20-23,29-33H,6-11,13-14H2,1-5H3/t16-,18-,20+,21-,22-,23+,24+,25+,26+,27+/m0/s1
• InChI key: PJYYBCXMCWDUAZ-JJJZTNILSA-N

Description

Application

Ponasterone A has been used to induce the expression of human huntingtin (HTT).

Suitable as an inducer of ecdysone-inducible mammalian expression system.

Biochem/physiol Actions

Ponasterone A is an analogue of ecdysone.

Ponasterone A is an insect hormone, involved in regulating metamorphosis.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves