S4776
Somatotropin from human pituitary
recombinant, expressed in E. coli, ≥95% (SDS-PAGE), lyophilized powder
Synonym(s):
Growth Hormone, STH
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About This Item
biological source:
human
form:
lyophilized powder
Recommended Products
biological source
human
Quality Level
recombinant
expressed in E. coli
sterility
non-sterile
Assay
≥95% (SDS-PAGE)
form
lyophilized powder
potency
0.025-0.1 ng/mL cell proliferation using Nb2-11 cells per bioactivity ED50
mol wt
predicted mol wt ~22 kDa
drug control
Home Office Schedule 4.2
impurities
endotoxin, tested
solubility
PBS: 0.100 mL, clear, colorless (with 0.1% BSA )
shipped in
ambient
storage temp.
−20°C
General description
Somatotropin or growth hormone is a peptide hormone that is secreted by the anterior pituitary gland. It is essential for growth. The hormone increases muscle mass, reduces fat mass, helps in maintaining normal blood glucose levels and also promotes a balanced lipid profile.
Application
Somatotropin or growth hormone has been used to study the molecular interactions of ephrin type-A receptor 4 precursor (EphA4) with the growth hormone receptor. It has also been used to induce differentiation in mammary epithelial cell line HC11.
Biochem/physiol Actions
Increases mass of most tissues by increasing cell number rather than cell size, mobilizes fat stores.
Physical form
Lyophilized from a 0.2 μm filtered solution in TBS (20 mM Tris, 0.15 M NaCl, pH 8.5) containing 50 μg of BSA per 1 μg of cytokine.
Reconstitution
It is recommended that sterile PBS containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of no less than 10 μg/mL.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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