S9944

Sibutramine hydrochloride monohydrate

≥98% (HPLC), solid

• Synonym(s): 1-(4-Chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)cyclobutanemethanamine hydrochloride monohydrate, Meridia, Reductil
• Empirical Formula (Hill Notation): C₁₇H₂₆ClN · HCl
• CAS Number: 84485-00-7
• Molecular Weight: 316.31
• MDL number: MFCD04039806
• UNSPSC Code: 12352116
• PubChem Substance ID: 329824638
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: solid
• drug control: USDEA Schedule IV
• storage condition: desiccated
• color: white
• solubility: DMSO: >30 mg/mL; H₂O: insoluble
• originator: Abbott
• storage temp.: room temp
• SMILES string: O.Cl.CC(C)CC(N(C)C)C1(CCC1)c2ccc(Cl)cc2
• InChI: 1S/C17H26ClN.ClH.H2O/c1-13(2)12-16(19(3)4)17(10-5-11-17)14-6-8-15(18)9-7-14;;/h6-9,13,16H,5,10-12H2,1-4H3;1H;1H2
• InChI key: KFNNPQDSPLWLCX-UHFFFAOYSA-N
• Gene Information: human ... SLC6A2(6530), SLC6A3(6531), SLC6A4(6532)

Description

Application

Sibutramine hydrochloride monohydrate was used as standard to screen dietary supplements for sibutramine using ion mobility spectrometer.¹

Biochem/physiol Actions

Sibutramine is a serotonin and noradrenaline reuptake inhibitor (SNRI).

Sibutramine is a serotonin and noradrenaline reuptake inhibitor (SNRI). It is an antiobesity drug, which decreases calorie intake and increases energy expanditure. Sibutramine antagonizes MPTP-induced dopamine depletion in mouse brain.

Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves