SAB4702151

Monoclonal Anti-CD300e, purified low endotoxin produced in mouse

• Synonym(s): CLM2, CMRF35-A5, IREM-2, LMIR6, PlgR2
• UNSPSC Code: 12352203

Properties

• conjugate: unconjugated
• Quality Level: 100
• antibody product type: primary antibodies
• clone: UP-H2, monoclonal
• form: buffered aqueous solution
• species reactivity: human
• concentration: 1 mg/ml
• technique(s): FUNC: suitable; flow cytometry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• isotype: IgG1κ
• UniProt accession no.: Q496F6
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: human ... CD300E(342510)

Description

General description

CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.

Specificity

The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.

Immunogen

CD300e-HA-transfected cells

Physical form

Phosphate buffered saline (PBS), pH 7.4

Preparation Note

Purified by protein-A affinity chromatography.

Storage and Stability

Store at 2-8°C. Do not freeze.

Other Notes

The antibody solution should be gently mixed before use.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable