SCP0153

GLP-1 (Preproglucagon 72-107 amide) (GLP-1 human)

• Empirical Formula (Hill Notation): C₁₈₄H₂₇₃N₅₁O₅₇
• Molecular Weight: 4111.44
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• Assay: ≥95% (HPLC)
• form: lyophilized
• composition: Peptide Content, ≥75%
• storage condition: protect from light
• storage temp.: −20°C

Description

Amino Acid Sequence

His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2

Application

GLP-1 (Preproglucagon 72-107 amide) (GLP-1 human) has been used to study its effect on vascular endothelial growth factor-A (VEGFA)-mediated endothelium-dependent signaling and vasodilation.

Glycogen-like peptide-1 (GLP-1) is an amino acid peptide derived from proglucogon. GLP-1 is involved in the regulation of the glycemic index via its affect on glucagon and insulin levels. GLP-1 may be used to study its interaction with its receptor, the GLP-1 receptor.

Biochem/physiol Actions

Glycogen-like peptide-1 (GLP-1) is an insulinotropic hormone, which takes part in increasing insulin secretion and insulin sensitivity. It also inhibits the secretion of glycogen and reduces fasting glucose levels.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable