SMB00705

Sesamin

≥98% (HPLC)

• Synonym(s): Fagarol
• Empirical Formula (Hill Notation): C₂₀H₁₈O₆
• CAS Number: 607-80-7
• Molecular Weight: 354.35
• MDL number: MFCD00216134
• UNSPSC Code: 12352205
• NACRES: NA.25

Properties

• Quality Level: 200
• Assay: ≥98% (HPLC)
• form: powder
• solubility: DMSO: 10 mg/mL
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: −20°C
• SMILES string: C1Oc2ccc(cc2O1)[C@H]3OC[C@H]4[C@@H]3CO[C@@H]4c5ccc6OCOc6c5
• InChI: 1S/C20H18O6/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19+,20+/m0/s1
• InChI key: PEYUIKBAABKQKQ-AFHBHXEDSA-N

Description

General description

Sesamin is the most abundant lignan isolated from Sesamum indicum or sesame seeds and sesame oil.

Application

Sesamin has been used as a reference standard to study the activity of Cytochrome P450 enzyme sesamin synthase from Sesamum indicum L. in the conversion of pinoresinol to sesamin.

Biochem/physiol Actions

Non-competitive Δ⁵-desaturase inhibitor.

Sesamin presents multiple health benefits including hypocholesterolemic, anti-hypertensive, anti-carcinogenic, anti-aging, immunoregulatory, hypoglycemic, anti-thrombotic, hepatoprotective, and antioxidant activities. It has also been demonstrated to work synergistically with vitamin E against lipid peroxidation. Sesamin was found to be metabolized into several catechol forms in the liver. These cathecols have a potent ability to scavenge superoxide radicals.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H317
• Precautionary Statements: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable