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Key Documents

SML0050

Sigma-Aldrich

CGP 37849

≥98% (HPLC)

Synonym(s):

(3E)-2-Amino-4-methyl-5-phosphono-3-pentanoic acid

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About This Item

Empirical Formula (Hill Notation):
C6H12NO5P
CAS Number:
Molecular Weight:
209.14
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: ≥2 mg/mL (warmed)

storage temp.

2-8°C

SMILES string

C\C(CP(O)(O)=O)=C/C(N)C(O)=O

InChI

1S/C6H12NO5P/c1-4(3-13(10,11)12)2-5(7)6(8)9/h2,5H,3,7H2,1H3,(H,8,9)(H2,10,11,12)/b4-2+

InChI key

BDYHNCZIGYIOGJ-DUXPYHPUSA-N

Application

CGP 37849 may be used in NMDA-mediated cell signaling studies.

Biochem/physiol Actions

CGP 37849 induces phencyclidine-like behavioral syndrome in amygdala-kindled rats that includes ataxia, locomotion and stereotypies.
CGP 37849 is a potent orally active competitive NMDA antagonist and anticonvulsant.
Potent orally active competitive NMDA antagonist and anticonvulsant.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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