SML0075

OBAA

≥98% (HPLC)

• Synonym(s): 3-(4-octadecyl)benzoylacrylic acid, 4-(4-octadecylphenyl)-4-oxo-2-Butenoic acid
• Empirical Formula (Hill Notation): C₂₈H₄₄O₃
• CAS Number: 134531-42-3
• Molecular Weight: 428.65
• UNSPSC Code: 41106300
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to tan
• solubility: DMSO: ≥5 mg/mL at 60 °C
• storage temp.: 2-8°C
• SMILES string: OC(=O)C=CC(=O)c1ccc(cc1)CCCCCCCCCCCCCCCCCC
• InChI: 1S/C28H44O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-25-19-21-26(22-20-25)27(29)23-24-28(30)31/h19-24H,2-18H2,1H3,(H,30,31)
• InChI key: ZBESASFHIWDSCJ-UHFFFAOYSA-N

Description

Application

OBAA may be used in PLA₂-mediated cell signaling studies.

Biochem/physiol Actions

OBAA is a PLA2 inhibitor

OBAA is a phospholipase A₂ inhibitor and prevents the melittin-induced influx of Ca⁺² in trypanosomes. It inhibits the generation of ROS when epithelial and endothelial cells are treated with cholic acid.

OBAA is a potent inhibitor of phospholipases.

Features and Benefits

This compound is featured on the Phospholipase A2 page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable