SML0224

HI-6

≥98% (HPLC)

• Synonym(s): 1-[[[4-(Aminocarbonyl)pyridinio]methoxy]methyl]-2-[(hydroxyimino)methyl]-pyridinium chloride, 4-Carbamoyl-1-[[[2-[(hydroxyimino)methyl]pyridinium-1-yl]methoxy]methyl]pyridinium dichloride, Asoxime chloride, HI 6, HI 6 chloride, HJ 6, Transant
• Empirical Formula (Hill Notation): C₁₄H₁₆N₄O₃ · 2Cl
• CAS Number: 34433-31-3
• Molecular Weight: 359.21
• MDL number: MFCD00869535
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825243
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: H₂O: 15 mg/mL (clear solution)
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: [Cl-].[Cl-].NC(=O)c1cc[n+](COC[n+]2ccccc2\C=N\O)cc1
• InChI: 1S/C14H14N4O3.2ClH/c15-14(19)12-4-7-17(8-5-12)10-21-11-18-6-2-1-3-13(18)9-16-20;;/h1-9H,10-11H2,(H-,15,19);2*1H
• InChI key: QELSIJXWEROXOE-UHFFFAOYSA-N

Description

General description

HI-6 functions as an antidote for treating intoxication caused by nerve agents. It acts as a potent drug in radiation protection and suppresses oxidative stress. HI-6 prevents the toxicity of the antineoplastic drug irinotecan.

Biochem/physiol Actions

HI-6 is an efficient oxime cholinesterase reactivator that is used as an antidote for organophosphates (Ops) exposure.

HI-6 is an efficient oxime cholinesterase reactivator.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable