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SML2193

Sigma-Aldrich

Altenusin

≥98% (HPLC)

Synonym(s):

3,4′,5′-Trihydroxy-5-methoxy-2′-methyl[1,1′-biphenyl]-2-carboxylic acid, Alutenusin

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About This Item

Empirical Formula (Hill Notation):
C15H14O6
CAS Number:
31186-12-6
Molecular Weight:
290.27
UNSPSC Code:
12352200
NACRES:
NA.77

biological source

Penicillium sp.

Assay

≥98% (HPLC)

form

powder

color

yellow to orange

storage temp.

−20°C

SMILES string

OC1=CC(C2=CC(OC)=CC(O)=C2C(O)=O)=C(C)C=C1O

InChI

1S/C15H14O6/c1-8-5-13(16)14(17)7-11(8)12-6-9(20-2)3-4-10(12)15(18)21-19/h3-7,16-17,19H,1-2H3

InChI key

GWGIZSANXIQQQR-UHFFFAOYSA-N

Biochem/physiol Actions

Altenusin, a non-steroidal fungal metabolite, is a potent and selective agonist of Farnesoid X receptor (FXR) that protects mice from high-fat diet induced obesity. Also it decreases blood glucose level, serum insulin level, and reduces lipid droplets accumulation. Altenusin inhibits trypanothione reductase from Trypanosoma cruzi.
potent and selective agonist of Farnesoid X receptor (FXR)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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