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Key Documents

SML2566

Sigma-Aldrich

CL097

≥98% (HPLC)

Synonym(s):

2-(Ethoxymethyl)-3H-imidazo[4,5-c]quinolin-4-amine, CL 097, CL-097

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About This Item

Empirical Formula (Hill Notation):
C13H14N4O
CAS Number:
Molecular Weight:
242.28
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

white to very dark brown

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

[nH]1c2c(nc1COCC)c(nc3c2cccc3)N

InChI

1S/C13H14N4O/c1-2-18-7-10-16-11-8-5-3-4-6-9(8)15-13(14)12(11)17-10/h3-6H,2,7H2,1H3,(H2,14,15)(H,16,17)

InChI key

DEVCLHVFELRPIU-UHFFFAOYSA-N

Biochem/physiol Actions

CL097 is an imidazoquinoline (IMDQ) derivative (IQD) with dual toll-like receptor 7 & 8 (TLR7 & TLR8; TLR7/8) agonist activity. CL097 is commonly employed in the concentration range from 0.5 μg/mL to 45 μg/mL for stimulating cell surface TLR7/8 in cultures and is reported to be a stronger TLR7 ligand than CL075.
Imidazoquinoline (IMDQ) derivative (IQD) with dual toll-like receptor 7 & 8 (TLR7 & TLR8; TLR7/8) agonist activity. A stronger TLR7 ligand than CL075.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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