T2903

Trp-His-Trp-Leu-Gln-Leu

≥97% (HPLC)

• Synonym(s): α₁-Mating factor fragment 1-6
• Empirical Formula (Hill Notation): C₄₅H₅₉N₁₁O₈
• CAS Number: 65418-88-4
• Molecular Weight: 882.02
• MDL number: MFCD00133882
• UNSPSC Code: 51111800
• PubChem Substance ID: 24900091
• NACRES: NA.32

Properties

• biological source: synthetic (organic)
• Quality Level: 200
• Assay: ≥97% (HPLC)
• form: powder
• storage temp.: −20°C
• SMILES string: CC(C)CC(NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc3cnc[nH]3)NC(=O)C(N)Cc4c[nH]c5ccccc45)C(O)=O
• InChI: 1S/C45H59N11O8/c1-24(2)15-35(42(60)52-34(13-14-39(47)57)41(59)56-38(45(63)64)16-25(3)4)54-43(61)36(18-27-21-50-33-12-8-6-10-30(27)33)55-44(62)37(19-28-22-48-23-51-28)53-40(58)31(46)17-26-20-49-32-11-7-5-9-29(26)32/h5-12,20-25,31,34-38,49-50H,13-19,46H2,1-4H3,(H2,47,57)(H,48,51)(H,52,60)(H,53,58)(H,54,61)(H,55,62)(H,56,59)(H,63,64)
• InChI key: PBLMMVDDGREFKH-UHFFFAOYSA-N

Description

Amino Acid Sequence

Trp-His-Trp-Leu-Gln-Leu

Application

Trp-His-Trp-Leu-Gln-Leu (WHWLQL) was used as an internal standard in multiplex serum protein assay for evaluating the individual′s probability of having colorectal cancer (CRC).

Biochem/physiol Actions

Trp-His-Trp-Leu-Gln-Leu (WHWLQL) is the peptide fragment of alpha1-mating factor secreted by yeast that facilitates in the regulation of mating. Alpha1-mating factor can arrest many yeast strains in the G1-phase of the cell cycle.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves