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T2943

Sigma-Aldrich

Tissue plasminogen activator chromogenic substrate

≥95% (HPLC), solid

Synonym(s):

TPA Activity Assay

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About This Item

MDL number:
UNSPSC Code:
12352204
NACRES:
NA.32

Quality Level

Assay

≥95% (HPLC)

form

solid

mol wt

apparent mol wt 658.9

solubility

methanol: water (1:9): 25 mg/mL

storage temp.

2-8°C

General description

Tissue plasminogen activator chromogenic substrate is a highly sensitive chromogenic peptide substrate for tissue plasminogen activator (tPA). It shows different sensitivity to native single-chain tPA (sc-tPA) and its fully active two-chain form (tc-tPA).

Application

Tissue plasminogen activator chromogenic substrate has been used:
  • in tissue plasminogen activator inhibition assay
  • to determine the plasminogen activator (PA) activity by studying the glycosylation properties of tissue plasminogen activator (tPA) activities in effusions using concanavalin A-Sepharose (conA-S) chromatography
  • in inhibition assays and complex formation analyses of wild type (WT) neuroserpin (NS) and its variants

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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