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T8441

Sigma-Aldrich

L-Threonine

99.0-101.0%, suitable for cell culture, BioXtra, non-animal source

Synonym(s):

(2S,3R)-2-Amino-3-hydroxybutyric acid

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About This Item

Linear Formula:
CH3CH(OH)CH(NH2)CO2H
CAS Number:
72-19-5
Molecular Weight:
119.12
Beilstein:
1721646
EC Number:
200-774-1
MDL number:
MFCD00064270
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24900531
NACRES:
NA.26
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Product Name

L-Threonine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

biological source

non-animal source

Quality Level

300

Agency

USP/NF
meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

product line

BioXtra

Assay

99.0-101.0%

form

powder

quality

meets EP, JP, USP testing specifications

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

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General description

L-Threonine is a naturally occurring amino acid belonging to the aspartate family of amino acids.[1]

Application

L-Threonine has been used for the following :
  • To study the effect of heat on homoserine kinase activity[2]
  • In Plackett–Burman analysis and then to study the effect of selected amino acids on monoclonal antibody production in CHO cells[3]
  • As a substrate to determine the L-threonine dehydrogenase activity[4]
  • To study the effect of L-Threonine on the growth rate of P. putida, to check for its tolerance towards L-Threonine[5]

Biochem/physiol Actions

L-Threonine is considered to be an essential amino acid. L-Threonine is involved in the synthesis of mucin, a protein supporting intestinal function and integrity. L-Threonine is required for the performance of the immune system. It is also essential for O-linked glycosylation, protein phosphorylation and glycine synthesis.[6]

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    SLCK1971
    SLCH6632
    SLCF7564
    SLCD1572
    SLBZ7810

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