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Supelco

Discovery® C8 (5 µm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

Synonym(s):

C8 Reversed-Phase Chromatography Column

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500000 UNITS
$221.00
1000000 UNITS
$367.00
5000000 UNITS
$1,570.00

$221.00


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500000 UNITS
$221.00
1000000 UNITS
$367.00
5000000 UNITS
$1,570.00

About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

$221.00


Please contact Customer Service for Availability

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Product Name

Discovery® C8 HPLC Column, 5 μm particle size, L × I.D. 15 cm × 4.6 mm

material

stainless steel column

Quality Level

Agency

suitable for USP L7

product line

Discovery®

feature

endcapped

manufacturer/tradename

Discovery®

packaging

1 ea of

extent of labeling

7.5% Carbon loading

parameter

≤70 °C temp. range
400 bar pressure (5801 psi)

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1 of 4

This Item
G0376G0799G7017
specific activity

≥1,000,000 units/g solid

specific activity

≥2,000,000 units/g solid

specific activity

>20,000,000 units/g protein

specific activity

≥100,000 units/mL

form

solid

form

solid

form

aqueous glycerol solution

form

aqueous solution

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

300

type

Type B-1

type

Type B-3

type

-

type

Type HP-2

Application

Discovery® C8 HPLC column has been used in the separation of fluoroquinolone antibiotics in tablets using reversed-phase high-performance liquid chromatography (RP-HPLC).

Features and Benefits

  • Excellent reproducibility
  • Faster separation of strongly hydrophobic analytes than C18 columns
  • Stable, low-bleed LC-MS separations
  • Exceptional peak shapes for basic and acidic compounds
  • Compatible with low organic/highly aqueous mobile phases

Legal Information

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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A D Fraser
Journal of analytical toxicology, 11(6), 263-266 (1987-11-01)
Alprazolam (Xanax) and triazolam (Halcion) are relatively new triazolobenzodiazepines that are anxiolytic and hypnotic. This study assesses the reactivity of these drugs and their major metabolites in the EMIT d.a.u. benzodiazepine metabolite assay. Analytical standards of drugs and metabolites and
Determination of furosemide with its acyl glucuronide in human plasma and urine by means of direct gradient high-performance liquid chromatographic analysis with fluorescence detection Preliminary pharmacokinetics and effect of probenecid
Vree TB, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 655(1), 53-62 (1994)
Uzma Salar et al.
European journal of medicinal chemistry, 125, 1289-1299 (2016-11-26)
Current study is based on the biology-oriented drug synthesis (BIODS) of 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl aryl carboxylate derivatives 1-26, by treating metronidazole with different aryl and hetero-aryl carboxylic acids in the presence of 1,1'-carbonyl diimidazole (CDI) as a coupling agent. Structures of all
P Jakobsen et al.
The Journal of pharmacy and pharmacology, 33(2), 89-92 (1981-02-01)
Sulphinpyrazone is an antiplatelet in vivo and in vitro. Two active metabolites, a sulphide (S) and a hydroxylated sulphide (S-OH) have been identified in rabbit and human plasma and a selective and sensitive g.c.-m.s.-method for quantitative determination of the sulphide
Zhe Shi et al.
British journal of pharmacology, 179(23), 5209-5221 (2022-07-31)
The constitutive androstane receptor (CAR), a known xenobiotic sensor, plays an important role in drug metabolism by regulating numerous genes. The polycyclic aromatic hydrocarbon pyrene, an environmental pollutant, is a CAR activator and induces mouse hepatotoxicity via CAR. Here, we

Protocols

Enzymatic Assay of ß-Glucuronidase (EC 3.2.1.31) from Helix Pomatia and Bovine Liver

To optimize hydrolysis using β-glucuronidase, factors such as incubation time, temperature, hydrolysis pH, enzyme source, and enzyme concentration must be evaluated for each glucuronide metabolite to be analyzed.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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