108448

Cyanoacetamide

99%

• Synonyme(s) : 2-Cyanoacetamide
• Formule linéaire : NCCH₂CONH₂
• CAS Number: 107-91-5
• Poids moléculaire : 84.08
• Beilstein: 878221
• Numéro CE : 203-531-8
• Numéro MDL: MFCD00008024
• Code UNSPSC : 12352100
• ID de substance PubChem : 24846668
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 200
• Essai: 99%
• Pf: 119-121 °C (lit.)
• Solubilité: cold water: soluble 1gm in 6.5ml
• Groupe fonctionnel: amide; nitrile
• Chaîne SMILES: NC(=O)CC#N
• InChI: 1S/C3H4N2O/c4-2-1-3(5)6/h1H2,(H2,5,6)
• Clé InChI: DGJMPUGMZIKDRO-UHFFFAOYSA-N

Description

Description générale

Cyanoacetamide is the starting reagent for vitamin B₆ synthesis. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence andis useful for the automated analysis of carbohydrates as borate complexes.

Cyanoacetamide is a highly reactive compound used as a reaction intermediate in condensation and substitution reactions.

Application

Cyanoacetamide was used in spectrofluorimetric method for the determination of some antihistaminic H₁ receptor antagonist drugs such as ebastine, cetirizine dihydrochloride and fexofenadine hydrochloride. It may be used in fluorometric determination of 3,4-dihydroxyphenylalanine. It was used as post column fluorigenic derivatizing agent for the bio-analysis and pharmacokinetics of chitosan ester in rabbit serum.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302,H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 419.0 °F - closed cup
• Point d'éclair (°C): 215 °C - closed cup
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves