115754

2,2,6,6-Tetramethylpiperidine

≥99%

• Synonyme(s) : 2,2,6,6-tetramethylpiperidide, 2,2,6,6-tetramethylpiperidine, Norpempidine, TEMP, TMPH
• Formule empirique (notation de Hill) : C₉H₁₉N
• CAS Number: 768-66-1
• Poids moléculaire : 141.25
• Beilstein: 103296
• Numéro CE : 212-199-3
• Numéro MDL: MFCD00005985
• Code UNSPSC : 12352005
• ID de substance PubChem : 24847237
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 200
• Essai: ≥99%
• Indice de réfraction: n20/D 1.445 (lit.)
• pb: 152 °C (lit.)
• Densité: 0.837 g/mL at 25 °C (lit.)
• Chaîne SMILES: CC1(C)CCCC(C)(C)N1
• InChI: 1S/C9H19N/c1-8(2)6-5-7-9(3,4)10-8/h10H,5-7H2,1-4H3
• Clé InChI: RKMGAJGJIURJSJ-UHFFFAOYSA-N

Description

Description générale

2,2,6,6-Tetramethylpiperidineis a hindered secondary amine that is used to prepare metallo-amide bases and selective generation of silylketene acetals.

Application

2,2,6,6-Tetramethylpiperidine can be used as a reactant to synthesize:

• Allylated tertiary amines via allylic amination of allylic chlorides.
• Hydroxylamines via oxidation in the presence of oxone as an oxidant.
• Sulfenamide compounds by reacting with heterocyclic thiols in the presence of iodine as an oxidant.
• N-methylated amines via N-methylation by reacting with CO₂ and phenylsilane.
• Propargylamines via three-component Mannich coupling reaction with aldehydes and alkynes.

Informations sur la sécurité

• Pictogrammes: GHS02,GHS05,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H226,H290,H302,H314,H335
• Conseils de prudence: P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Met. Corr. 1 - Skin Corr. 1A - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 98.6 °F - closed cup
• Point d'éclair (°C): 37 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter