125180

1-(3-Chlorophenyl)piperazine hydrochloride

99%

• Synonyme(s) : m-CPP
• Formule empirique (notation de Hill) : C₁₀H₁₃ClN₂ · xHCl
• CAS Number: 65369-76-8
• Poids moléculaire : 196.68 (free base basis)
• Numéro CE : 265-718-0
• Numéro MDL: MFCD00039032
• Code UNSPSC : 12352100
• ID de substance PubChem : 24847652
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Essai: 99%
• Forme: powder
• Pf: 210-214 °C (dec.) (lit.)
• Solubilité: methanol: soluble
• Groupe fonctionnel: chloro
• Chaîne SMILES: Cl.Clc1cccc(c1)N2CCNCC2
• InChI: 1S/C10H13ClN2.ClH/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13;/h1-3,8,12H,4-7H2;1H
• Clé InChI: MHXPYWFZULXYHT-UHFFFAOYSA-N
• Informations sur le gène: rat ... Htr1a(24473)

Description

Description générale

1-(3-Chlorophenyl)piperazine hydrochloride is sold as Ecstasy mimic tablets and is the major metabolite of the antidepressant medications trazodone and nefazodone.

Application

1-(3-Chlorophenyl)piperazine hydrochloride (CPP) has been used in determination of designer piperazines in urine specimens using GC-MS and LC-ESI-MS. CPP has been used to investigate the in vitro efficacy of newly synthesized compounds such as fluoroquinolones (norfloxacine and lomefloxacine) against Philasterides dicentrarchi .

Actions biochimiques/physiologiques

1-(3-Chlorophenyl)piperazine induces hypophagia in food-deprived and freely feeding rats. CPP has affinity for 11 neurotransmitter receptor binding sites in human brain membranes.

5-HT_2c serotonin receptor agonist; metabolite of trazodone.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302,H315,H319,H335
• Conseils de prudence: P261 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Faceshields, Gloves