157449

β-Bromostyrene

97%

• Synonyme(s) : beta-Bromostyrene, 1-Bromo-2-phenylethylene
• Formule linéaire : C₆H₅CH=CHBr
• CAS Number: 103-64-0
• Poids moléculaire : 183.05
• Beilstein: 2038495
• Numéro CE : 203-131-3
• Numéro MDL: MFCD00000185
• Code UNSPSC : 12352100
• ID de substance PubChem : 24849679
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Essai: 97%
• Forme: liquid
• Indice de réfraction: n20/D 1.607 (lit.)
• pb: 110-112 °C/20 mmHg (lit.)
• Pf: 7 °C (lit.)
• Densité: 1.427 g/mL at 25 °C (lit.)
• Groupe fonctionnel: bromo; phenyl
• Température de stockage: 2-8°C
• Chaîne SMILES: Br\C=C\c1ccccc1

Description

Description générale

β-Bromostyrene is an α,β-unsaturated aromatic halide. It can be synthesized by catalytic Hunsdiecker reaction (CHR) of cinnamic acid. It is commonly utilized as a precursor for preparing substituted alkenes, corresponding acetylenes and also in the total synthesis of natural compounds and antibiotics.

Application

β-Bromostyrene was used in the one-pot method for the preparation of cinnamonitriles. It was also used in the preparation of pure ethyl Z- and E-α,α-difluoro-4-phenyl-3-butenoate and 1,3-diphenyl-1-butene. It may be used in the synthesis of β-tert-butylstyrene via cross coupling reaction with tert-butylmagnesium chloride in the presence of dichloro[1,1′-bis(diphenylphosphino)ferrocene]nickel(II) catalyst. It may also be used to prepare γ-but-2-enolactone by reacting with nickel carbonyl in the presence of alkynes.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302
• Classification des risques: Acute Tox. 4 Oral
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 215.6 °F - closed cup
• Point d'éclair (°C): 102 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter