193984

1-Methylindole

≥97%

• Synonyme(s) : NSC 212534
• Formule empirique (notation de Hill) : C₉H₉N
• CAS Number: 603-76-9
• Poids moléculaire : 131.17
• Beilstein: 111026
• Numéro CE : 210-057-5
• Numéro MDL: MFCD00005800
• Code UNSPSC : 12352100
• ID de substance PubChem : 24851625
• Nomenclature NACRES : NA.22

Propriétés

• Essai: ≥97%
• Forme: liquid
• Indice de réfraction: n20/D 1.606 (lit.)
• pb: 133 °C/26 mmHg (lit.)
• Densité: 1.051 g/mL at 20 °C (lit.)
• Chaîne SMILES: Cn1ccc2ccccc12
• InChI: 1S/C9H9N/c1-10-7-6-8-4-2-3-5-9(8)10/h2-7H,1H3
• Clé InChI: BLRHMMGNCXNXJL-UHFFFAOYSA-N

Description

Description générale

1-Methylindole undergoes Au(III)/TPPMS-catalyzed benzylation reaction with benzhydryl and benzylic alcohols.

Application

1-Methylindole was used in the determination of association constant for the electron-donor-acceptor complexes of 1-methylindole with 1-(2,4,6-trinitrophenyl) propan-2-one.

Reactant for preparation of:

• Pharmaceutically active 2-oxo-1-pyrrolidine analogues
• Non-receptor tyrosine kinase (Src kinase) inhibitors
• PET agents for imaging of protein kinase C (PKC)
• Ynediones as highly reactive Michael systems
• Anticancer agents
• Polycyclic derivatives of indoles
• PET agents for imaging of glycogen synthase kinase-3 (GSK-3)
• Anti-prion disease agents
• Bisindole derivatives with antihyperlipidemic activity
• PET cancer imaging agents

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 235.4 °F - closed cup
• Point d'éclair (°C): 113 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)