195421

10,11-Dihydrocarbamazepine

99%

• Synonyme(s) : 10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide
• Formule empirique (notation de Hill) : C₁₅H₁₄N₂O
• CAS Number: 3564-73-6
• Poids moléculaire : 238.28
• Numéro CE : 222-649-0
• Numéro MDL: MFCD00005072
• Code UNSPSC : 12352100
• ID de substance PubChem : 24851693
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Essai: 99%
• Forme: solid
• Pf: 205-210 °C (lit.)
• Solubilité: dichloromethane: soluble 2.5%, clear, colorless
• Groupe fonctionnel: amine
• Chaîne SMILES: NC(=O)N1c2ccccc2CCc3ccccc13
• InChI: 1S/C15H14N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-8H,9-10H2,(H2,16,18)
• Clé InChI: PHNLCHMJDSSPDQ-UHFFFAOYSA-N

Description

Description générale

10,11-Dihydrocarbamazepine is an impurity present in dibenzazepine drug used in the treatment of epilepsy. Single-crystal structure of new dimer-based polymorph of 10,11-dihydrocarbamazepine has been investigated.

Application

10,11-Dihydrocarbamazepine was used as internal standard during simultaneous determination of carbamazepine and its active metabolite in plasma by liquid chromatography. It was used in chemiluminescence method for determination of carbamazepine.

Informations sur la sécurité

• Pictogrammes: GHS08,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H302,H317,H336,H360D
• Conseils de prudence: P201 - P280 - P301 + P312 + P330 - P302 + P352 - P308 + P313
• Classification des risques: Acute Tox. 4 Oral - Repr. 1A - Skin Sens. 1A - STOT SE 3
• Organes cibles: Central nervous system
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable