284270

Phosphonoacetic acid

98%

• Synonyme(s) : (Carboxymethyl)phosphonic acid, 2-Phosphonoacetic acid, Fosfonoacetic acid, Phosphonacetic acid
• Formule linéaire : (HO)₂P(O)CH₂CO₂H
• CAS Number: 4408-78-0
• Poids moléculaire : 140.03
• Numéro CE : 224-558-1
• Numéro MDL: MFCD00004311
• Code UNSPSC : 12352100
• ID de substance PubChem : 24857145
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Essai: 98%
• Forme: powder or crystals
• Pf: 143-146 °C (lit.)
• Solubilité: water: soluble 100 mg/mL, clear to very slightly hazy, colorless
• Groupe fonctionnel: carboxylic acid
• Chaîne SMILES: OC(=O)CP(O)(O)=O
• InChI: 1S/C2H5O5P/c3-2(4)1-8(5,6)7/h1H2,(H,3,4)(H2,5,6,7)
• Clé InChI: XUYJLQHKOGNDPB-UHFFFAOYSA-N

Description

Description générale

Phosphonoacetic acid inhibits specifically human cytomegalovirus DNA synthesis in virus-infected human fibroblasts. It also inhibits the synthesis of herpes simplex virus DNA in infected cells and the activity of the virus-specific DNA polymerase in vitro.

Application

Phosphonoacetic acid was used as an inhibitor of viral DNA replication, to investigate the infected cell protein 0 (bICP0) localization in infected low passage bovine cells. It was also used as a phosphorus source for microbial growth in phosphate-independent manner.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves