286583

5-Methoxytryptamine

97%

• Synonyme(s) : 2-(5-Methoxyindol-3-yl)ethylamine, 3-(2-Aminoethyl)-5-methoxyindole, 5-MOT, 5-Methoxyindole-3-ethanamine, Deacetylmelatonin, NSC 56422
• Formule empirique (notation de Hill) : C₁₁H₁₄N₂O
• CAS Number: 608-07-1
• Poids moléculaire : 190.24
• Beilstein: 145587
• Numéro CE : 210-153-7
• Numéro MDL: MFCD00005662
• Code UNSPSC : 12352100
• ID de substance PubChem : 24857245
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 200
• Essai: 97%
• Forme: solid
• Pf: 121-123 °C (lit.)
• Groupe fonctionnel: amine
• Chaîne SMILES: COc1ccc2[nH]cc(CCN)c2c1
• InChI: 1S/C11H14N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3
• Clé InChI: JTEJPPKMYBDEMY-UHFFFAOYSA-N
• Informations sur le gène: human ... HTR1A(3350), HTR2A(3356), HTR2C(3358) ; rat ... Htr2a(29595), Htr2c(25187), Htr7(65032)

Description

Description générale

The protective effect of 5-methoxytryptamine (a metabolite of melatonin) in human keratinocytes against ultraviolet B (UVB) radiation was studied.

Application

5-Methoxytryptamine was used as an agonist in the study of pharmacological profile of the 5-hydroxytryptamine 1 receptor.

Reactant for preparation of:

• Carboline disaccharide domain of shishijimicin A
• Melatonin analogs for the reduction of intraocular pressure
• 5-HT4 receptor ligands
• inhibitors of sortase A and isocitrate lyase
• Therapeutic agents for treatment of ischemia/reperfusion (I/R) injury
• Aurora and epidermal growth factor receptor kinase inhibitors
• Agents for the treatment of human papillomavirus infection
• Manzamine analogues for the control of neuroinflammation and cerebral infections
• Inhibitors of pro-inflammatory cytokines
• Tacrine-melatonin hybrids as multifunctional agents for alzheimer′s disease

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302
• Conseils de prudence: P264 - P270 - P301 + P312 - P501
• Classification des risques: Acute Tox. 4 Oral
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves