361518

1-Hydroxypyrene

98%

• Synonyme(s) : 1-Pyrenol
• Formule empirique (notation de Hill) : C₁₆H₁₀O
• CAS Number: 5315-79-7
• Poids moléculaire : 218.25
• Numéro MDL: MFCD00044543
• Code UNSPSC : 12352100
• ID de substance PubChem : 24862229
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Essai: 98%
• Pf: 179-182 °C (lit.)
• Chaîne SMILES: Oc1ccc2ccc3cccc4ccc1c2c34
• InChI: 1S/C16H10O/c17-14-9-7-12-5-4-10-2-1-3-11-6-8-13(14)16(12)15(10)11/h1-9,17H
• Clé InChI: BIJNHUAPTJVVNQ-UHFFFAOYSA-N

Description

Description générale

1-Hydroxypyrene, as a urinary metabolite, is a marker of polycyclic aromatic hydrocarbons (PAH) exposure. 1-Hydroxypyrene is an important biomarker of exposure to pyrene.

Application

1-Hydroxypyrene is suitable for use in following studies:

• To investigate the fast detection and quantification of 1-hydroxypyrene in tissue extracts from Nereis diversicolor exposed to sediment-associated pyrene by a simple fluorometric method.
• To investigate the effects of genetic polymorphisms of the cytochrome P450 1A1 (CYP1A1) and 2E1 (CYP2E1) and glutathione S-transferases mu (GSTM1) and theta (GSTT1) on urinary 1-hydroxypyrene and 2-naphthol levels in aircraft maintenance workers.
• To examine the the PAH exposure of cokery workers in an Estonian oil shale processing plant.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves