383449

3-Formylchromone

97%

• Synonyme(s) : 4-Oxo-4H-1-benzopyran-3-carboxaldehyde
• Formule empirique (notation de Hill) : C₁₀H₆O₃
• CAS Number: 17422-74-1
• Poids moléculaire : 174.15
• Numéro CE : 241-451-5
• Numéro MDL: MFCD00014667
• Code UNSPSC : 12352100
• ID de substance PubChem : 24863967
• Nomenclature NACRES : NA.22

Propriétés

• Essai: 97%
• Forme: solid
• Pf: 151-153 °C (lit.)
• Groupe fonctionnel: aldehyde; ketone
• Chaîne SMILES: O=CC1=COc2ccccc2C1=O
• InChI: 1S/C10H6O3/c11-5-7-6-13-9-4-2-1-3-8(9)10(7)12/h1-6H
• Clé InChI: FSMYWBQIMDSGQP-UHFFFAOYSA-N
• Informations sur le gène: human ... PTPN1(5770)

Description

Description générale

Electrospray ionization mass spectrometry (ESI-MS) of protonated 3-formylchromone (3-FC) shows loss of H₂ as a major fragmentation route to yield a ketene cation, which on reaction with water forms a protonated carboxylic acid. The invivo salubrious effects of 3-FC against nitrosodiethylamine (NDEA) mediated early hepatocellular carcinogenesis has been investigated. Synthesis and characterization of 3-FC and its derivatives has been reported.

Application

3-Formylchromone may be used in the following studies:

• Preparation of library of novel (E)-3-(2-arylcarbonyl-3-(arylamino)allyl)-4H-chromen-4-ones, by three-component domino reactions with (E)-3-(dimethylamino)-1-arylprop-2-en-1-ones and anilines under catalyst-free conditions.
• Facile and ecofriendly synthesis of new chromonyl chalcones.
• Synthesis of 3-(2-hydroxybenzoyl)quinolines and 7H-chromeno[3,2-c]quinolin-7-ones.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)