39391

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide

≥97.0% (T), for peptide synthesis

• Synonyme(s) : N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide, EDC, WSC
• Formule empirique (notation de Hill) : C₈H₁₇N₃
• CAS Number: 1892-57-5
• Poids moléculaire : 155.24
• Beilstein: 507429
• Numéro CE : 217-579-2
• Numéro MDL: MFCD00044916
• Code UNSPSC : 12352116
• ID de substance PubChem : 57649895
• Nomenclature NACRES : NA.22

Propriétés

• Product Name: N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide, ≥97.0% (T)
• Essai: ≥97.0% (T)
• Forme: liquid
• Capacité de réaction: reaction type: Coupling Reactions
• Indice de réfraction: n20/D 1.461
• Densité: 0.877 g/mL at 20 °C (lit.)
• Application(s): peptide synthesis
• Groupe fonctionnel: amine
• Température de stockage: −20°C
• Chaîne SMILES: CCN=C=NCCCN(C)C
• InChI: 1S/C8H17N3/c1-4-9-8-10-6-5-7-11(2)3/h4-7H2,1-3H3
• Clé InChI: LMDZBCPBFSXMTL-UHFFFAOYSA-N

Description

Description générale

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide is commonly used in combination with N-hydroxysuccinimide (NHS) in carbodiimide coupling reaction to activate carboxyl group for coupling with amines to form amides.

Application

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide has been used for the surface functionalization of graphene quantum dots (GQDs) employed as sensing probes in Janus micromotors to detect enterobacterial contamination. It has also been used for the activation of folic acid, prior to its conjugation on silica nanoparticles.

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08,GHS05,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H302,H311,H314,H317,H373,H410
• Conseils de prudence: P273 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338 - P314
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1A - STOT RE 2 Oral
• Organes cibles: Stomach,large intestine,lymph node
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter