405957

Tris(1,1,1,3,3,3-hexafluoro-2-propyl) phosphite

98%

• Synonyme(s) : Tris(2H-perfluoro-2-propyl) phosphite
• Formule linéaire : [(CF₃)₂CHO]₃P
• CAS Number: 66470-81-3
• Poids moléculaire : 532.06
• Beilstein: 2315565
• Numéro MDL: MFCD00192561
• Code UNSPSC : 12352100
• ID de substance PubChem : 24865342
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Essai: 98%
• Forme: liquid
• Indice de réfraction: n20/D 1.300 (lit.)
• pb: 130 °C (lit.)
• Densité: 1.69 g/mL at 25 °C (lit.)
• Groupe fonctionnel: fluoro
• Chaîne SMILES: FC(F)(F)C(OP(OC(C(F)(F)F)C(F)(F)F)OC(C(F)(F)F)C(F)(F)F)C(F)(F)F
• InChI: 1S/C9H3F18O3P/c10-4(11,12)1(5(13,14)15)28-31(29-2(6(16,17)18)7(19,20)21)30-3(8(22,23)24)9(25,26)27/h1-3H
• Clé InChI: MJOVEPJSFHDSOJ-UHFFFAOYSA-N

Description

Description générale

Tris(1,1,1,3,3,3-hexafluoro-2-propyl) phosphite (tris(1,1,1,3,3,3-hexafluoroisopropyl) phosphite) is a sterically hindered, weakly σ-donating and strongly π-accepting ligand. It can be prepared by the reaction of lithium salt of 1,1,1,3,3,3-hexafluoro-2-propoxide with PCl₃. It reacts with nucleosides to form deoxyribonucleoside 3′-bis(1,1,1,3,3,3-hexafluoro-2-propyl) phosphite units.

Application

Tris(1,1,1,3,3,3-hexafluoro-2-propyl) phosphite (tris(1,1,1,3,3,3-hexafluoroisopropyl) phosphite) may be used in the following processes:

• Preparation of new phosphonylating and coupling agents for the synthesis of oligodeoxyribonucleotides.
• Preparation of nucleoside H-phosphonate units.
• Synthesis of tetrakis(1,1,1,3,3,3-hexafluoroisopropoxy)(phenylthio)phosphorane by reacting with 1,1,1,3,3,3-hexafluoroisopropyl benzenesulfenate.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type ABEK (EN14387) respirator filter