412422

PAMAM dendrimer, ethylenediamine core, generation 3.0 solution

20 wt. % in methanol

• Synonyme(s) : Starburst PAMAM-G 3
• Formule linéaire : [NH₂(CH₂)₂NH₂]:(G=3);dendri PAMAM(NH₂)₃₂
• CAS Number: 153891-46-4
• Poids moléculaire : 6908.84
• Numéro MDL: MFCD00197936
• Code UNSPSC : 12162002
• Nomenclature NACRES : NA.23

Propriétés

• Description: amino surface groups
• Niveau de qualité: 100
• Forme: liquid
• Poids mol.: generation 3.0
• Caractéristiques: core type ethylenediamine core (2-carbon core)
• Concentration: 20 wt. % in methanol
• Nb de groupes de surface: 32
• Indice de réfraction: n20/D 1.367
• pb: 64.7 °C
• Densité: 0.863 g/mL at 25 °C
• Température de stockage: 2-8°C

Description

Description générale

PAMAM dendrimer is a symmetrical polymer with a large number of terminal groups that can easily bind to biomolecules due to their biocompatibility and affinity. These dendrimers have a multivalent surface that contains envelopes and various active sites at the core with the attached dendrons. They are highly branched nanoscale polymers that are extensively used in the field of biomedicine for targeted drug delivery.

Application

PAMAM dendrimers can be used as transfection agents for the delivery of nucleic acids. For example, it can be used in the pulmonary delivery of siRNA directed against tumor necrosis factor (TNF).

Forme physique

Contains 32 surface primary amino groups

Informations légales

Manufactured by Dendritech^®, Inc.

Dendritech is a registered trademark of Dendritech, Inc.

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H225,H301 + H311 + H331,H370
• Conseils de prudence: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organes cibles: Eyes,Central nervous system
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 51.8 °F - closed cup
• Point d'éclair (°C): 11 °C - closed cup