513830

Indole-5-carboxaldehyde

98%

• Synonyme(s) : 5-Formylindole
• Formule empirique (notation de Hill) : C₉H₇NO
• CAS Number: 1196-69-6
• Poids moléculaire : 145.16
• Numéro MDL: MFCD02093664
• Code UNSPSC : 12352100
• ID de substance PubChem : 24873717
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Essai: 98%
• Pf: 100-103 °C (lit.)
• Groupe fonctionnel: aldehyde
• Chaîne SMILES: O=Cc1ccc2[nH]ccc2c1
• InChI: 1S/C9H7NO/c11-6-7-1-2-9-8(5-7)3-4-10-9/h1-6,10H
• Clé InChI: ADZUEEUKBYCSEY-UHFFFAOYSA-N

Description

Application

Indole-5-carboxaldehyde can be used as a reactant in the:

• Preparation of curcumin derivatives as anti-proliferative & anti-inflammatory agents
• Preparation of analogs of botulinum neurotoxin serotype A protease inhibitors
• Stereoselective synthesis of dibenzylideneacetone derivatives as β-amyloid imaging probes
• Synthesis of para-para stilbenophanes by McMurry coupling
• Stereoselective synthesis of heteroaromatic (E)-α,β-unsaturated ketones from aldehydes
• Structure-based drug design of aurora kinase A inhibitors
• Preparation of 5-indolyl linked 15- and 18-membered azacrown ethers to study their cation-π interactions.
• Preparation of bibenzimidazole derivatives substituted 5-indolyl moiety in the study of inhibition of topoisomerase I activity.
• Synthesis of (5-(4-(3,4,5-trimethoxybenzoyl)-1H-imidazol-2-yl)-1H-indol-2-yl)(3,4,5-trimethoxyphenyl)methanone and radioiodinated indolochalcone.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves