790451

TCO-amine HCl salt

• Synonyme(s) : trans-Cyclooctene-amine hydrochloride salt, TCO-NH2, HCl salt
• Formule empirique (notation de Hill) : C₁₂H₂₂N₂O₂ · HCl
• Poids moléculaire : 262.78
• Numéro MDL: MFCD31692192
• Code UNSPSC : 12352116
• ID de substance PubChem : 329768216
• Nomenclature NACRES : NA.22

Propriétés

• Forme: solid
• Niveau de qualité: 100
• Capacité de réaction: reaction type: click chemistry
• Pertinence de la réaction: reagent type: linker
• Groupe fonctionnel: amine
• Température de stockage: −20°C
• Chaîne SMILES: O=C(NCCCN)OC1CCC/C=C/CC1.[H]Cl
• InChI: 1S/C12H22N2O2.ClH/c13-9-6-10-14-12(15)16-11-7-4-2-1-3-5-8-11;/h1-2,11H,3-10,13H2,(H,14,15);1H/b2-1+;
• Clé InChI: GIYQQURLGCGUKK-TYYBGVCCSA-N

Description

Application

Amine functionalized trans-cyclooctene derivative for incorporation of the cyclooctene moiety into carboxyl containing compounds or biomolecules via standard coupling techniques (DCC; EDC etc...). Trans-cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1; 2; 4; 5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302
• Classification des risques: Acute Tox. 4 Oral
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable