900914

Methyltetrazine-NHS ester

≥95%

• Synonyme(s) : 2,5-Dioxo-1-pyrrolidinyl 4-(6-methyl-1,2,4,5-tetrazin-3-yl)benzeneacetate
• Formule empirique (notation de Hill) : C₁₅H₁₃N₅O₄
• CAS Number: 1644644-96-1
• Poids moléculaire : 327.29
• Numéro MDL: MFCD28334557
• Code UNSPSC : 12352108
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Essai: ≥95%
• Forme: powder or crystals
• Capacité de réaction: reaction type: click chemistry
• Pertinence de la réaction: reagent type: cross-linking reagent
• Groupe fonctionnel: NHS ester
• Température de stockage: −20°C
• Chaîne SMILES: O=C(ON1C(CCC1=O)=O)CC(C=C2)=CC=C2C3=NN=C(C)N=N3
• InChI: 1S/C15H13N5O4/c1-9-16-18-15(19-17-9)11-4-2-10(3-5-11)8-14(23)24-20-12(21)6-7-13(20)22/h2-5H,6-8H2,1H3
• Clé InChI: BIHJLZOOHNOUCG-UHFFFAOYSA-N

Description

Application

Methyltetrazine-NHS ester has an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines and a methyltetrazine, which is reactive to trans-cyclooctenes. The NHS ester reacts with primary amines (e.g. side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds. The short spacer arm adds minimal mass to modified molecules (230.2 daltons). It is generally used in click chemistry applications in bioconjugate chemistry.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable