924229

(S,R,S)-AHPC-Me

95%

• Synonyme(s) : (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide, PROTAC^® research ligand, VH032 methyl derivative
• Formule empirique (notation de Hill) : C₂₃H₃₂N₄O₃S
• CAS Number: 1948273-02-6
• Poids moléculaire : 444.59
• Numéro MDL: MFCD31630815
• Code UNSPSC : 12352101
• Nomenclature NACRES : NA.22

Propriétés

• ligand: VH032
• Niveau de qualité: 100
• Essai: 95%
• Forme: powder
• Température de stockage: 2-8°C
• Chaîne SMILES: C([C@H](C(C)(C)C)N)(=O)N1[C@H](C(N[C@@H](C)C2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1
• InChI: 1S/C23H32N4O3S/c1-13(15-6-8-16(9-7-15)19-14(2)25-12-31-19)26-21(29)18-10-17(28)11-27(18)22(30)20(24)23(3,4)5/h6-9,12-13,17-18,20,28H,10-11,24H2,1-5H3,(H,26,29)/t13-,17+,18-,20+/m0/s1
• Clé InChI: JOSFQWNOUSNZBP-UUZHKXTQSA-N

Description

Application

(S,R,S)-AHPC-Me is a VH032 derivative used in the recruitment of the von Hippel-Lindau (VHL) protein for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This was previously listed under ATEH961B8E6E.

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Informations légales

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable