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ANV00025

Sigma-Aldrich

3-Aminoisoquinoline

Synonyme(s) :

Isoquinolin-3-amine

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About This Item

Formule empirique (notation de Hill) :
C9H8N2
CAS Number:
25475-67-6
Poids moléculaire :
144.17
Numéro MDL:
MFCD00102190
Code UNSPSC :
12352200
ID de substance PubChem :
329772819
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Forme

solid

Pf

174-178 °C

Chaîne SMILES 

Nc1cc2ccccc2cn1

InChI

1S/C9H8N2/c10-9-5-7-3-1-2-4-8(7)6-11-9/h1-6H,(H2,10,11)

Clé InChI

VYCKDIRCVDCQAE-UHFFFAOYSA-N

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Cet article
730513136107CDS020140
3-Aminoisoquinoline

ANV00025

3-Aminoisoquinoline

3-Aminoisoquinoline 97%

730513

3-Aminoisoquinoline

5-Aminoisoquinoline 99%

136107

5-Aminoisoquinoline

8-Aminoisoquinoline AldrichCPR

CDS020140

8-Aminoisoquinoline

mp

174-178 °C

mp

174-178 °C

mp

125-128 °C (lit.)

mp

-

form

solid

form

solid

form

-

form

solid

Autres remarques

Please note that Sigma-Aldrich provides this product to early discovery researchers as part of a collection of unique chemicals. Sigma-Aldrich does not collect analytical data for this product. Buyer assumes responsibility to confirm product identity and/or purity. All sales are final.

NOTWITHSTANDING ANY CONTRARY PROVISION CONTAINED IN SIGMA-ALDRICH′S STANDARD TERMS AND CONDITIONS OF SALE OR AN AGREEMENT BETWEEN SIGMA-ALDRICH AND BUYER, SIGMA-ALDRICH SELLS THIS PRODUCT "AS-IS" AND MAKES NO REPRESENTATION OR WARRANTY WHATSOEVER WITH RESPECT TO THIS PRODUCT, INCLUDING ANY (A) WARRANTY OF MERCHANTABILITY; (B) WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE; OR (C) WARRANTY AGAINST INFRINGEMENT OF INTELLECTUAL PROPERTY RIGHTS OF A THIRD PARTY; WHETHER ARISING BY LAW, COURSE OF DEALING, COURSE OF PERFORMANCE, USAGE OF TRADE OR OTHERWISE.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302,H315,H319,H335

Classification des risques

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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    Rui Sun et al.
    Molecular & cellular proteomics : MCP, 16(10), 1789-1800 (2017-08-18)
    4-Oxo-2-nonenal (ONE) derived from lipid peroxidation modifies nucleophiles and transduces redox signaling by its reactions with proteins. However, the molecular interactions between ONE and complex proteomes and their dynamics in situ remain largely unknown. Here we describe a quantitative chemoproteomic
    Diana A Quintero-Espinosa et al.
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    It is increasingly evident that LRRK2 kinase activity is involved in oxidative stress (OS)-induced apoptosis-a type of regulated cell death and neurodegeneration, suggesting LRRK2 inhibition as a potential therapeutic target. We report that a phenolic-rich extract of avocado Persea americana
    Yuichiro Mita et al.
    Scientific reports, 8(1), 12056-12056 (2018-08-15)
    DJ-1 plays an important role in antioxidant defenses, and a reactive cysteine at position 106 (Cys106) of DJ-1, a critical residue of its biological function, is oxidized under oxidative stress. DJ-1 oxidation has been reported in patients with Parkinson's disease
    Katalin Solti et al.
    Neurobiology of disease, 134, 104629-104629 (2019-11-02)
    The loss of native function of the DJ-1 protein has been linked to the development of Parkinson's (PD) and other neurodegenerative diseases. Here we show that DJ-1 aggregates into β-sheet structured soluble and fibrillar aggregates in vitro under physiological conditions
    Viviana Soto-Mercado et al.
    PloS one, 15(5), e0221669-e0221669 (2020-05-22)
    Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive memory loss and cognitive disturbance as a consequence of the loss of cholinergic neurons in the brain, neuritic plaques and hyperphosphorylation of TAU protein. Although the underlying mechanisms leading to
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