D97703

Diethyl maleate

97%

• Synonyme(s) : Maleic acid diethyl ester
• Formule linéaire : C₂H₅OCOCH=CHCOOC₂H₅
• CAS Number: 141-05-9
• Poids moléculaire : 172.18
• Beilstein: 1100825
• Numéro CE : 205-451-9
• Numéro MDL: MFCD00009191
• Code UNSPSC : 12352100
• ID de substance PubChem : 24894328
• Nomenclature NACRES : NA.22

Propriétés

• Densité de vapeur: 5.93 (vs air)
• Niveau de qualité: 100
• Pression de vapeur: 1 mmHg ( 14 °C)
• Essai: 97%
• Forme: liquid
• Température d'inflammation spontanée: 662 °F
• Indice de réfraction: n20/D 1.441 (lit.)
• pb: 225 °C (lit.)
• Pf: −10 °C (lit.)
• Densité: 1.064 g/mL at 25 °C (lit.)
• Chaîne SMILES: CCOC(=O)\C=C/C(=O)OCC
• InChI: 1S/C8H12O4/c1-3-11-7(9)5-6-8(10)12-4-2/h5-6H,3-4H2,1-2H3/b6-5-
• Clé InChI: IEPRKVQEAMIZSS-WAYWQWQTSA-N

Description

Description générale

Diethyl maleate is an ester derived from maleic anhydride, used as a building block in the synthesis of pyromellitic acid.

Application

• Retrospective analysis of pesticide metabolites in urine using liquid chromatography coupled to high-resolution mass spectrometry.: This study highlights the use of diethyl maleate in the analysis of pesticide metabolites, demonstrating its application in high-resolution mass spectrometry for detecting urinary pesticide metabolites (Lapez et al., 2016).


• Diethyl maleate inhibits MCA+TPA transformed cell growth via modulation of GSH, MAPK, and cancer pathways.: Research on the inhibition of cancer cell growth by diethyl maleate, focusing on its effects on glutathione, MAPK pathways, and its potential therapeutic applications in cancer treatment (Priya et al., 2014).


• Hepatic transcriptome and proteome responses against diethyl maleate-induced glutathione depletion in the rat.: This study explores the effects of diethyl maleate on liver cells, emphasizing its role in depleting glutathione and its implications for oxidative stress and liver toxicity (Yamauchi et al., 2011).


• Application of the BIRD sandwich for the rapid and accurate determination of (1)H-(1)H NMR coupling constants in higher order spin systems.: This paper discusses the innovative application of diethyl maleate in NMR spectroscopy for accurate determination of coupling constants, enhancing the analysis of complex spin systems (Williamson et al., 2000).

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H317,H319,H412
• Conseils de prudence: P273 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 200.1 °F - closed cup
• Point d'éclair (°C): 93.4 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Gloves, type ABEK (EN14387) respirator filter