P26252

Phenylhydrazine

97%

• Synonyme(s) : Hydrazinobenzene, Monophenylhydrazine
• Formule linéaire : C₆H₅NHNH₂
• CAS Number: 100-63-0
• Poids moléculaire : 108.14
• Beilstein: 606080
• Numéro CE : 202-873-5
• Numéro MDL: MFCD00007573
• Code UNSPSC : 12352100
• ID de substance PubChem : 24898342
• Nomenclature NACRES : NA.22

Propriétés

• Densité de vapeur: 4.3 (vs air)
• Niveau de qualité: 200
• Pression de vapeur: <0.1 mmHg ( 20 °C)
• Essai: 97%
• Température d'inflammation spontanée: 345 °F
• Indice de réfraction: n20/D 1.607 (lit.)
• pb: 238-241 °C (lit.)
• Pf: 18-21 °C (lit.)
• Densité: 1.098 g/mL at 25 °C (lit.)
• Chaîne SMILES: NNc1ccccc1
• InChI: 1S/C6H8N2/c7-8-6-4-2-1-3-5-6/h1-5,8H,7H2
• Clé InChI: HKOOXMFOFWEVGF-UHFFFAOYSA-N

Description

Application

Phenylhydrazine can be used as a reactant in the synthesis of:

• 4, 4′-(arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)s by reacting with aryl aldehydes and acetoacetates in presence of N-bromo sulfonamide as a catalyst via one-pot pseudo-five-component condensation.
• Thiazolidinones by treating with mercaptoacetic acid and aldehydes or ketones.
• 5-[3,3,3-trifluoro-2-(phenylhydrazono)propyl]-1-phenyl-1H-pyrazole-3-carboxylic acid by reacting with 6-(trifluoromethyl)comanic acid.

It can be also used as a precursor for the preparation of selective carboxymethylated products at N-1 and N-2 by reacting with dimethyl carbonate (DMC) in the presence of a Bronsted base and metal salts as a catalyst.

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H301 + H311 + H331 - H315 - H317 - H319 - H341 - H350 - H372 - H400
• Conseils de prudence: P273 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1
• Code de la classe de stockage: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 192.2 °F - closed cup
• Point d'éclair (°C): 89 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter