840514C

16:0-18:1 Phosphatidylethanol

Avanti Research^™ - A Croda Brand 840514C

• Synonyme(s) : 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol (sodium salt)
• Formule empirique (notation de Hill) : C₃₉H₇₄NaO₈P
• CAS Number: 322647-55-2
• Poids moléculaire : 724.96
• Code UNSPSC : 12352211
• Nomenclature NACRES : NA.25

Propriétés

• Essai: >99% (TLC)
• Forme: liquid
• Conditionnement: pkg of 1 × 2.5 mL (840514C-25mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand 840514C
• Concentration: 10 mg/mL (840514C-25mg)
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [H][C@@](COP([O-])(OCC)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
• InChI: 1S/C39H75O8P.Na/c1-4-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-39(41)47-37(36-46-48(42,43)45-6-3)35-44-38(40)33-31-29-27-25-23-21-18-16-14-12-10-8-5-2;/h19-20,37H,4-18,21-36H2,1-3H3,(H,42,43);/q;+1/p-1/b20-19-;/t37-;/m1./s1
• Clé InChI: JFUGSRIBTPUDOW-VYMFHCNISA-M

Description

Description générale

Phosphatidylethanol (PEth) is a phospholipid, that is generated in the the presence of ethanol in cell membranes. PEths like PEth 16:0/18:1, PEth 18:1/18:1, and PEth 16:0/16:0 possesses a common phosphoethanol head. Two fatty acid chains of variable length and degree of saturation are bound to this head group. It is widely distributed in gram-positive organisms.

Phosphatidylethanol (PEth) represents a group of glycerophospholipid homologues generated by substitution of ethanol for the lipid headgroup by the phospholipase D enzyme. Since the formation of PEth is specifically dependent on ethanol, the diagnostic specificity of PEth as an alcohol biomarker is theoretically 100%.

Application

16:0-18:1 Phosphatidylethanol is suitable for use in the preparation of liposomes used for permeability studies.

Actions biochimiques/physiologiques

Phosphatidylethanols (PEths) serves as crucial biomarkers of alcohol consumption.

Conditionnement

5 mL Clear Glass Sealed Ampule (840514C-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Conseils de prudence: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Classification des risques: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Organes cibles: Central nervous system, Liver,Kidney
• Classe de danger pour l'eau (WGK): WGK 3