850459C

16:0-20:4 PC

Avanti Research^™ - A Croda Brand

• Synonyme(s) : 1-hexadecanoyl-2--(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine; PAPC; PC(16:0/20:4(5Z,8Z,11Z,14Z))
• Formule empirique (notation de Hill) : C₄₄H₈₀NO₈P
• CAS Number: 35418-58-7
• Poids moléculaire : 782.08
• Numéro MDL: MFCD00171671
• Code UNSPSC : 51191904
• Nomenclature NACRES : NA.25

Propriétés

• Description: 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine, chloroform
• Essai: >99% (TLC)
• Forme: liquid
• Conditionnement: pkg of 1 × 2.5 mL (850459C-25mg); pkg of 2 × 4 mL (850459C-200mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand
• Concentration: 10 mg/mL (850459C-25mg); 25 mg/mL (850459C-200mg)
• Type de lipide: cardiolipins; phospholipids
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCC)COC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC)OCC[N+](C)(C)C
• InChI: 1S/C44H80NO8P/c1-6-8-10-12-14-16-18-20-21-22-23-25-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-24-19-17-15-13-11-9-7-2/h14,16,20-21,23,25,28,30,42H,6-13,15,17-19,22,24,26-27,29,31-41H2,1-5H3/b16-14-,21-20-,25-23-,30-28-/t42-/m1/s1
• Clé InChI: PUDHBQQGURLBGJ-IVFHWKNFSA-N

Description

Description générale

Phosphatidylcholine (PC) is one of the major glycerophospholipids of the eukaryotic membranes. PC is zwitterionic. PC is synthesized via two pathways in higher eukaryotes like the triple methylation of phosphatidylethanolamine and the cytidine diphosphate (CDP)-choline pathway.

Application

16:0-20:4 PC is suitable for use:

• in the preparation of auto-oxidised phospholipid for electrospray ionisation mass spectroscopic (ESI-MS) analysis
• in liposome preparation for the treatment of organoid
• as antigen in enzyme linked immunosorbent assay (ELISA) for the detection of autoantibodies to phospholipids

Actions biochimiques/physiologiques

Phosphatidylcholine (PC) is essential for maintaining the structure and functions of the membrane. PC is the substrate for sphingomyelin synthesis. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol. PC is the dominant phospholipid present in cancer and neo-neoplastic tissues. Level of 16:0-20:4 PC is less in multiple myeloma cells than in normal plasma cells.

Conditionnement

5 mL Clear Glass Sealed Ampule (850459C-200mg)

5 mL Clear Glass Sealed Ampule (850459C-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Conseils de prudence: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Classification des risques: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Organes cibles: Central nervous system, Liver,Kidney
• Code de la classe de stockage: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): does not flash
• Point d'éclair (°C): does not flash