860674P

Sphinganine (d20:0)

Avanti Research^™ - A Croda Brand 860674P, powder

• Synonyme(s) : D-erythro-sphinganine (C20 base)
• Formule empirique (notation de Hill) : C₂₀H₄₃NO₂
• CAS Number: 24006-62-0
• Poids moléculaire : 329.56
• Numéro MDL: MFCD08703033
• Code UNSPSC : 12352211
• Nomenclature NACRES : NA.25

Propriétés

• Forme: powder
• Conditionnement: pkg of 1 × 5 mg (860674P-5mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand 860674P
• Type de lipide: sphingolipids
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: OC[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCCCCC
• InChI: 1S/C20H43NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)19(21)18-22/h19-20,22-23H,2-18,21H2,1H3/t19-,20+/m0/s1
• Clé InChI: UFMHYBVQZSPWSS-VQTJNVASSA-N

Description

Description générale

Sphinganine (d20:0), also known as C20 dihydrosphingosine or icosasphinganine, is a C20 analog of sphinganine. Sphinganine is a derivative of sphingosine. It is formed in endoplasmic reticulum, by decarboxylating condensation of palmitoyl-CoA and serine.

Application

Sphinganine (d20:0) has been used as a standard in gas chromatography-mass spectrometry (GC-MS) for the quantitative analysis of plant sphingolipid long-chain bases.

Actions biochimiques/physiologiques

Sphinganine (d20:0) is implicated in yeast heat stress adaptation. Sphinganine inhibits protein kinase C in intact human neutrophils. It might act as a biomarker for the diagnosis of sphingolipidoses. It inhibits cholesterol transport in Niemann-Pick Type C (NPC) disease.

Conditionnement

5 mL Amber Glass Screw Cap Vial (860674P-5mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3