860679P

C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z))

Avanti Research^™ - A Croda Brand 860679P, powder

• Synonyme(s) : N-nervonoyl-D-erythro-sphingosine (d7)
• Formule empirique (notation de Hill) : C₄₂H₇₄D₇NO₃
• CAS Number: 1840942-16-6
• Poids moléculaire : 655.14
• Numéro MDL: MFCD35061399
• Code UNSPSC : 12352100
• Nomenclature NACRES : NA.25

Propriétés

• Forme: powder
• Conditionnement: pkg of 1 × 1 mg (860679P-1mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand 860679P
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: OC[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@@](O)([H])/C=C/CCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H]
• Clé InChI: VJSBNBBOSZJDKB-PVDQZAGSSA-N

Description

Description générale

C24:1 Ceramide (d18:1/24:1) is a synthetic ceramide derived from sphingosine with nervonic acid (a monounsaturated analog of lignoceric acid (24:0)). C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z)) is a deuterated derivative of C24:1 Ceramide (d18:1/24:1).

Application

C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z)) has been used as a standard in liquid chromatography–mass spectrometry (LC-MS) for quantitative analysis of C24:1 ceramide in skeletal muscle. It has also been used as a standard to measure C40-C44 ceramides in zebrafish brain and human embryonic kidney cell line (HEK293) by thermo q-exactive plus quadrupole-orbitrap mass spectrometery.

Actions biochimiques/physiologiques

Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios in human plasma aids the prognosis of fatal outcome of coronary artery disease. C24:1 Ceramide (d18:1/24:1) in a stable isotope form is suitable for a newly described validated liquid chromatography-tandem mass spectrometry methodology for their clinical-scaled measurement.

Conditionnement

5 mL Amber Glass Screw Cap Vial (860679P-1mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Point d'éclair (°F): No data available
• Point d'éclair (°C): No data available