870601C

Azelaoyl-PAF

Avanti Research^™ - A Croda Brand 870601C

• Synonyme(s) : 1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine
• Formule empirique (notation de Hill) : C₃₃H₆₆NO₉P
• CAS Number: 354583-69-0
• Poids moléculaire : 651.85
• Numéro MDL: MFCD03412018
• Code UNSPSC : 12352211
• Nomenclature NACRES : NA.25

Propriétés

• Forme: liquid
• Conditionnement: pkg of 1 × 1 mL (870601C-1mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand 870601C
• Concentration: 1 mg/mL (870601C-1mg)
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC(O)=O)=O)COCCCCCCCCCCCCCCCC)=O
• InChI: 1S/C33H66NO9P/c1-5-6-7-8-9-10-11-12-13-14-15-16-20-23-27-40-29-31(30-42-44(38,39)41-28-26-34(2,3)4)43-33(37)25-22-19-17-18-21-24-32(35)36/h31H,5-30H2,1-4H3,(H-,35,36,38,39)/t31-/m1/s1
• Clé InChI: ZDFOCDTXDPKJKA-WJOKGBTCSA-N

Description

Description générale

1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine (Azelaoyl-PAF) Azelaoyl-PAF is an alkyl phosphatidylcholine and is a component of the lipid pool within oxidized low-density lipoprotein (oxLDL) particles. Azelaoyl-PAF is a low molecular weight phospholipid.

Application

Azelaoyl-PAF may be used in binding assay of anti-inflammatory peptides, 2F and 4F.

Actions biochimiques/physiologiques

1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine (Azelaoyl-PAF) acts as an agonist for peroxisome proliferator-activated receptors γ(PPAR-γ). It may be used as a therapeutic for Friedreich′s ataxia (FRDA). At low concentrations azelaoyl-PAF may induce apoptosis.

Conditionnement

5 mL Clear Glass Sealed Ampule (870601C-1mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Conseils de prudence: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Classification des risques: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Organes cibles: Central nervous system, Liver,Kidney
• Classe de danger pour l'eau (WGK): WGK 3