E-068

Everolimus solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Formule empirique (notation de Hill) : C₅₃H₈₃NO₁₄
• CAS Number: 159351-69-6
• Poids moléculaire : 958.22
• Numéro MDL: MFCD00929329
• Code UNSPSC : 41116107
• ID de substance PubChem : 329798983
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Niveau de qualité: 300
• Forme: liquid
• Caractéristiques: (Snap-N-Spike^®)
• Conditionnement: ampule of 1 mL
• Fabricant/nom de marque: Cerilliant^®
• Concentration: 1.0 mg/mL in acetonitrile
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Application(s): clinical testing
• Format: single component solution
• Conditions d'expédition: dry ice
• Température de stockage: −70°C
• Chaîne SMILES: N21[C@@H](CCCC2)C(=O)O[C@@H](CC(=O)[C@@H](\C=C(\[C@H]([C@H](C(=O)[C@@H](C[C@@H](\C=C\C=C\C=C(\[C@H](C[C@H]4O[C@]([C@@H](CC4)C)(C(=O)C1=O)O)OC)/C)C)C)OC)O)/C)C)[C@@H](C[C@H]3C[C@H]([C@@H](CC3)OCCO)OC)C
• InChI: 1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/b13-11+,16-12+,33-17+,37-27+/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1
• Clé InChI: HKVAMNSJSFKALM-GKUWKFKPSA-N
• Informations sur le gène: human ... FKBP1A(2280)

Description

Description générale

Everolimus, sold under trade names including Zortress^®, Certican, and Afinitor^®, is an immunosuppressant drug used to prevent rejection of organ transplants and to treat renal cell cancer and other tumors. This Certified Spiking Solution^® is suitable as starting material for calibrators, controls, or linearity standards for therapeutic drug monitoring or clinical and diagnostic testing of everolimus in patient whole blood samples by LC-MS/MS.

Informations légales

Afinitor is a registered trademark of Novartis AG

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Zortress is a registered trademark of Novartis AG

Informations sur la sécurité

• Pictogrammes: GHS02,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H225,H302 + H312 + H332,H319
• Conseils de prudence: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 35.6 °F - closed cup
• Point d'éclair (°C): 2.0 °C - closed cup