05-786

Anti-phospho-SMC1 (Ser957) Antibody, clone 5D11G5

clone 5D11G5, Upstate^®, from mouse

• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 100
• Forme d'anticorps: purified antibody
• Type de produit anticorps: primary antibodies
• Clone: 5D11G5, monoclonal
• Espèces réactives: mouse, human
• Fabricant/nom de marque: Upstate^®
• Technique(s): western blot: suitable
• Isotype: IgG1
• Numéro d'accès NCBI: NM_006306
• Numéro d'accès UniProt: Q14683
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: phosphorylation (pSer957)
• Informations sur le gène: human ... SMC1A(8243)

Description

Description générale

SMC1 is a ATPase and subunit of the multiprotein cohesin complex, a protein involved in chromosome segregation and in double-strand DNA break (DSB) repair. Serine 957 is phosphorylated by ATM in response to DSBs and is involved in the S-phase DNA damage checkpoint.

Spécificité

Predicted to cross-react with xenopus and bovine based on sequence homology

phospho-SMC1 (Ser957)

Immunogène

KLH-conjugated, synthetic peptide corresponding to amino acids 951-962 (SQEEGS[pS]QGEDS) of human SMC1

Application

Detect phospho-SMC1 (Ser957) with Anti-phospho-SMC1 (Ser957) Antibody, clone 5D11G5 (Mouse Monoclonal Antibody), that has been shown to work in WB.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Cell Cycle, DNA Replication & Repair

Qualité

routinely evaluated by immunoblot on RIPA lysates from irradiated GMO536 cells and hydroxyurea treated HEK293 cells

Description de la cible

Mr 150kDa

Forme physique

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%

Format: Purified

Protein G Purified

Stockage et stabilité

2 years at -20°C

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable