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205546

Sigma-Aldrich

Caffeic Acid

A natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties.

Synonyme(s) :

Caffeic Acid, 3,4-Dihydroxycinnamic Acid

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About This Item

Formule empirique (notation de Hill) :
C9H8O4
CAS Number:
Poids moléculaire :
180.16
Numéro MDL:
Code UNSPSC :
12352106
Nomenclature NACRES :
NA.77

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Niveau de qualité

Description

Merck USA index - 14, 1635

Essai

≥95% (HPLC)

Forme

crystalline solid

Fabricant/nom de marque

Calbiochem®

Conditions de stockage

OK to freeze

Couleur

tan

Solubilité

DMSO: 200 mg/mL
ethanol: 50 mg/mL

Conditions d'expédition

ambient

Température de stockage

2-8°C

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Cet article
205548C0625324683
Caffeic Acid A natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties.

205546

Caffeic Acid

Caffeine Trimethylated xanthine that acts as a potent central nervous system stimulant.

205548

Caffeine

Caffeic acid ≥98.0% (HPLC)

C0625

Caffeic acid

assay

≥95% (HPLC)

assay

≥99% (HPLC)

assay

≥98.0% (HPLC)

assay

≥98% (HPLC)

form

crystalline solid

form

solid

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

100

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

Calbiochem®

storage temp.

2-8°C

storage temp.

10-30°C

storage temp.

-

storage temp.

10-30°C

storage condition

OK to freeze

storage condition

OK to freeze

storage condition

-

storage condition

OK to freeze, protect from light

Description générale

A cell-permeable natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties. A selective, non-competitive inhibitor of 5-lipoxygenase (ID50 = 3.7 µM). Inhibits Cu2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An effective irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.
A natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties. A cell-permeable, selective, non-competitive inhibitor of 5-lipoxygenase (ID50 = 3.7 µM). Inhibits Cu2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.

Actions biochimiques/physiologiques

Cell permeable: yes
Primary Target
5-lipoxygenase
Product does not compete with ATP.
Reversible: no
Target IC50: 3.7 µM against 5-lipoxygenase

Conditionnement

Packaged under inert gas

Avertissement

Toxicity: Carcinogenic / Teratogenic (D)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Autres remarques

Yamanaka, N., et al. 1997. FEBS Lett.405, 186.
Chan, W.S., et al. 1995. Anticancer Res.15, 703.
Ploemen, J.H., et al. 1993. Food Chem. Toxicol.31, 475.
Koshihara, Y., et al. 1984. Biochim. Biophys. Acta792, 92.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

Health hazard

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Carc. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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