3867

Hydrocortisone

Steroid hormone of the adrenal cortex with anti-inflammatory properties.

• Synonyme(s) : Hydrocortisone, Cortisol
• Formule empirique (notation de Hill) : C₂₁H₃₀O₅
• CAS Number: 50-23-7
• Poids moléculaire : 362.46
• Numéro MDL: MFCD00011654
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Description: RTECS - GM8925000; Merck USA index - 14, 4787
• Niveau de qualité: 100
• Essai: ≥98% (TLC)
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze
• Couleur: white to off-white
• Solubilité: ethanol: 15 mg/mL
• Conditions d'expédition: ambient
• Température de stockage: 10-30°C
• Chaîne SMILES: O[C@]1([C@@]2([C@H]([C@H]3[C@@H]([C@]4(CCC(=O)C=C4CC3)C)[C@H](C2)O)CC1)C)C(=O)CO
• InChI: 1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
• Clé InChI: JYGXADMDTFJGBT-VWUMJDOOSA-N

Description

Description générale

Steroid hormone of the adrenal cortex with anti-inflammatory properties.

Steroid synthesized by the adrenal cortex. Important in the regulation of protein, nucleic acid, and lipid metabolism. Pharmacologically, hydrocortisone is used to suppress the inflammatory response.

Actions biochimiques/physiologiques

Cell permeable: no

Primary Target
Steroid hormone of the adrenal cortex with anti-inflammatory properties

Product does not compete with ATP.

Reversible: no

Avertissement

Toxicity: Carcinogenic / Teratogenic (D)

Notes préparatoires

Heating to 37°C may be required for complete solubilization.

Reconstitution

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 1 month at 4°C.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H360Df,H373
• Conseils de prudence: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Classification des risques: Repr. 1A - STOT RE 2
• Organes cibles: Adrenal gland,Bone marrow
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable