5.05222

RuBi-Nicotine

• Synonyme(s) : RuBi-Nicotine, Bis(2,2′-bipyridine-N,N′)bis(S-nicotine-N1) ruthenium(2+) dichloride complex Bis(2,2ʹ-bipyridine-N,Nʹ)bis(S-nicotine-N1) ruthenium(2+) dichloride complex , Nicotinic Cholinergic Receptor Agonist, RuBi-Nicotine, nAChR Receptor Agonist, RuBi-Nico
• Formule empirique (notation de Hill) : C₄₀H₄₄Cl₂N₈Ru
• CAS Number: 1256362-30-7
• Poids moléculaire : 808.81
• Numéro MDL: MFCD22989497
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Essai: ≥98% (NMR)
• Niveau de qualité: 100
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; protect from light
• Couleur: deep orange
• Solubilité: H₂O: 100 mM
• Température de stockage: −20°C
• Chaîne SMILES: [Ru+2]85([NH]9=CC=CC=C9C%10=CC=CC=[NH]%108)([NH]6=CC=CC=C6C7=CC=CC=[NH]75)([NH]3=CC=CC(=C3)[C@H]4N(CCC4)C)[NH]1=CC=CC(=C1)[C@H]2N(CCC2)C.[Cl-].[Cl-]
• InChI: 1S/2C10H14N2.2C10H8N2.2ClH.Ru/c2*1-12-7-3-5-10(12)9-4-2-6-11-8-9;2*1-3-7-11-9(5-1)10-6-2-4-8-12-10;;;/h2*2,4,6,8,10H,3,5,7H2,1H3;2*1-8H;2*1H;/q;;;;;;+2/p-2/t2*10-;;;;;/m00...../s1
• Clé InChI: BQXVYFYPLMVART-ZPFSJBFKSA-L

Description

Description générale

A highly water soluble Ruthenium-bisbipyridine-caged nicotine that can be un-caged by blue and green light. Rapid nicotine release (<20 ns) and fast biological effects in vivo.

Actions biochimiques/physiologiques

Primary Target
nAChR

Avertissement

Toxicity: Toxic (F)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months.

Autres remarques

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Filevich, O., et al. 2010. J. Inorg. Biochem.104, 51.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS06,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H301 - H310 - H410
• Conseils de prudence: P262 - P264 - P273 - P280 - P301 + P310 - P302 + P352 + P310
• Classification des risques: Acute Tox. 1 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2
• Code de la classe de stockage: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable