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MILLIPLEX® Non-Human Primate Cytokine/Chemokine/Growth Factor Panel A 48-Plex Premixed Magnetic Bead Panel

Synonyme(s) :

48-Plex Cytokine Beads, Cytokine Magnetic Bead Panel, Primate Cytokine Panel

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1 G
196 300 KRW
5 G
394 100 KRW
10 G
835 800 KRW

196 300 KRW


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1 G
196 300 KRW
5 G
394 100 KRW
10 G
835 800 KRW

About This Item

Code UNSPSC :
12352200
Nomenclature NACRES :
NA.47

196 300 KRW


Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit.

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Espèces réactives

nonhuman primates

assay range

accuracy: 80-102%
inter-assay cv: <20%
intra-assay cv: <10%

inter-assay cv: <30%
(TNF-α)

Technique(s)

multiplexing: suitable

Méthode de détection

fluorometric (Luminex® MAP)

Conditions d'expédition

wet ice

Température de stockage

2-8°C

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Cet article
211605450308208299
form

crystals, powder and chunks

form

powder, crystals or chunks

form

powder and chunks

form

solid

assay

99.999% trace metals basis

assay

99.9% trace metals basis

assay

99.99% trace metals basis

assay

98%

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

vapor pressure

0.01 mmHg ( 20 °C)

vapor pressure

-

vapor pressure

-

vapor pressure

10 mmHg ( 656 °C)

impurities

≤15.0 ppm Trace Metal Analysis

impurities

≤1500.0 ppm Trace Rare Earth Analysis

impurities

≤30.0 ppm Trace Metal Analysis

impurities

-

density

2.15 g/mL at 25 °C (lit.)

density

-

density

1.69 g/mL at 25 °C (lit.)

density

3.327 g/mL at 25 °C (lit.)

Description générale

“Cytokine” is a general term used for a diverse group of small proteins, peptides or glycoproteins secreted by lymphocytes, monocytes, macrophages and other cells that regulate immune responses, haematopoiesis and lymphocyte development. Cytokines include interleukins, interferons, chemokines and other signaling molecules. Growth factors are extracellular polypeptides that have a positive effect on cell growth and proliferation. They can stimulate growth in a variety of different cell types. Growth factors and cytokines are similar in structure and the way of action. Individual cytokines or growth factors are produced by multiple cell types. This is different from hormones, which tend to be made by specialized glands. Each cytokine or growth factor acts through its own receptor on target cells to generate signaling pathways, and as a consequence to regulate biological processes. Some intracellular signaling components are shared between cytokines and growth factors. Expression of cytokines or growth factors and their receptors is highly regulated. De-regulation may contribute to many diseases such as infectious disease, autoimmune and chronic inflammatory disease, cardiovascular disease, metabolic syndrome, neurological disorders and cancer. Cytokine and growth factor research plays a significant role in achieving a deeper understanding of the immune system and combating related diseases. As the most closely related species to humans, non-human primates are critical models for those studies.
The MILLIPLEX® Non-Human Primate Cytokine/Chemokine/Growth Factor Panel A 48-Plex Premixed Magnetic Bead Panel is a 48-plex kit to be used for the simultaneous quantification of the following analytes in serum or plasma samples and tissue/cell lysate and culture supernatant samples: BCA-1, sCD137, sCD40L, Eotaxin, sFASL, FGF-2, Fractalkine, G-CSF, GM-CSF, Granzyme A, Granzyme B, IFNa2, IFN?, IL-1a, IL-1ß, IL-1RA, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p70), IL-15, IL-16, IL-17A, IL-17E, IL-18, IL-21, IL-22, IL-23, IL-28A, IL-31, IL-33, IP-10, I-TAC, MCP-1, MIG, MIP-1a, MIP-1ß, MIP-3a, Perforin, RANTES, TGFa, TNFa, TNFß, VEGF-A.

Spécificité

There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel, except G-CSF had ~5% cross-reactivity with IL-1ß.

Application

  • Analytes: BCA-1, sCD137, CD40L, Eotaxin, sFASL, FGF-2, Fractalkine, G-CSF, GM-CSF, Granzyme A, Granzyme B, IFN?2, IFN?, IL-1?, IL-1?, IL-1RA, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p70), IL-15, IL-16, IL-17A, IL-17E, IL-18, IL-21, IL-22, IL-23, IL-28A, IL-31, IL-33, IP-10, I-TAC, MCP-1, MIG, MIP-1?, MIP-1?, MIP-3?, Perforin, RANTES, TGF?, TNF?, TNF?, VEGF-A
  • Recommended Sample type: Serum, plasma or tissue/cell lysate and culture supernatant samples
  • Recommended Sample dilution: Neat plasma or serum. Tissue culture supernatant may require a dilution with an appropriate control medium prior to assay. RANTES requires a 1:100 dilution of plasma/serum samples.

NOTE: RANTES cannot be plexed with other cytokines in this panel due to a required 1:100 dilution of plasma/serum samples. This premixed panel comes with a RANTES bead, so please plan your samples accordingly.
Note: The serum/plasma samples of some non-human primate species may require up to 1:100 dilution in Assay Buffer for IL-8.
  • Assay Run Time: Overnight or two-hour primary incubation. For best results, an overnight incubation is recommended
  • Research Category: Inflammation & Immunology
  • Research Sub Category: Obesity, Metabolic Disorders, Inflammation & Autoimmune Mechanisms

Caractéristiques et avantages

Configuration: Premixed

Stockage et stabilité

  • Recommended storage for kit components is 2 - 8°C.
  • For long-term storage, freeze reconstituted standards and controls at -20°C. Avoid multiple freeze/thaw cycles.
  • DO NOT FREEZE Antibody-Immobilized Beads, Detection Antibody, and Streptavidin-Phycoerythrin.

Informations légales

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

Organes cibles

Respiratory Tract

Code de la classe de stockage

10 - Combustible liquids


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    T M Bayless et al.
    The New England journal of medicine, 292(22), 1156-1159 (1975-05-29)
    We studied 166 hospitalized male patients to determine the clinical importance of tolerance-test-determined "lactose intolerance," assumed to affect most of the world's adults. Abnormal lactose tolerance tests were found in 81% of 98 blacks, 12% of 59 whites of Scandinavian
    P Wong et al.
    Biotechnology progress, 13(2), 132-143 (1997-03-01)
    A mathematical model of the lactose (lac) operon was developed to study diauxic growth on glucose and lactose. The model includes catabolite repression, inducer exclusion, lactose hydrolysis to glucose and galactose, and synthesis and degradation of allolactose. Two models for
    C L Wells et al.
    Infection and immunity, 55(11), 2689-2694 (1987-11-01)
    It is thought that the normal enteric microflora acts not only to prevent intestinal colonization but also to prevent subsequent systemic dissemination of ingested, potentially pathogenic bacteria. To determine the relative roles of specific components of the intestinal bacterial flora
    Lactose intolerance following extensive small intestinal resection.
    A J Richards et al.
    The British journal of surgery, 58(7), 493-494 (1971-07-01)
    J Boya et al.
    Journal of anatomy, 175, 229-236 (1991-04-01)
    A lectin-histochemical study on microglial development has been performed on the rat central nervous system. Isolectin B4 from the Griffonia simplicifolia (GSA I-B4) and Ricinus communis agglutinin-120 (RCA-1) were used as labelling lectins. Our results demonstrate the existence of microglial

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