14690

Bis(cyclohexanone)oxaldihydrazone

for spectrophotometric det. of Cu, ≥99.0%

• Synonyme(s) : Cuprizon, Cuprizone, Oxalic acid bis(cyclohexylidenehydrazide)
• Formule empirique (notation de Hill) : C₁₄H₂₂N₄O₂
• CAS Number: 370-81-0
• Poids moléculaire : 278.35
• Beilstein: 2388004
• Numéro CE : 206-729-2
• Numéro MDL: MFCD00001659
• Code UNSPSC : 41116105
• ID de substance PubChem : 329750579
• Nomenclature NACRES : NA.21

Propriétés

• Niveau de qualité: 100
• Essai: ≥99.0% (N); ≥99.0%
• Forme: powder
• Qualité: for spectrophotometric det. of Cu
• Technique(s): UV/Vis spectroscopy: suitable
• Pf: 210-214 °C (lit.); 210-214 °C
• Chaîne SMILES: O=C(N\N=C1\CCCCC1)C(=O)N\N=C2/CCCCC2
• InChI: 1S/C14H22N4O2/c19-13(17-15-11-7-3-1-4-8-11)14(20)18-16-12-9-5-2-6-10-12/h1-10H2,(H,17,19)(H,18,20)
• Clé InChI: DSRJIHMZAQEUJV-UHFFFAOYSA-N

Description

Description générale

Cuprizone (Bis(cyclohexanone)oxaldihydrazone) is a physically unstable compound and is a well-known neurotoxic agent.

Application

Cuprizone (Bis(cyclohexanone)oxaldihydrazone) was used for toxic demyelination in the central nervous system in order to investigate the pathobiology of remyelination in the corpus callosum, so as to study the human demyelinating diseases such as multiple sclerosis. It was also used a model to study components of neuroinflammation.

Autres remarques

For the spectrophotometric determination of Cu(II)

In the presence of a copper salt, this ligand catalyzes Ullmann-type C-N bond forming reactions under mild, aqueous conditions.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)